LIM and Senescent Cell Antigen-Like Domains 2 (LIMS2) (C-Term) antibody

Antigen: LIM and Senescent Cell Antigen-Like Domains 2 (LIMS2)

Binding Site: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Please enquire

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN657520

Additional Information

Alternative name: LIMS2

Gene ID: 55679

UniProt: NP_001154875.1, NP_060450.2, NP_001129509.2, Q7Z4I7, NP_001154876.1

Immunogen: This LIMS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-337 amino acids from the C-terminal region of human LIMS2.

Isotype: Ig

Description: Other names: LIM and senescent cell antigen-like-containing domain protein 2,LIMS2,PINCH2

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This LIMS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-337 amino acids from the C-terminal region of human LIMS2.

Molecular Weight: 38916 DA

Comments:

Background: LIMS2 is a focal adhesion protein that associates with integrin-linked kinase (ILK, MIM 602366), a multidomain protein that mediates multiple protein-protein interactions at adhesion sites between cells and the extracellular matrix (ECM).[supplied by OMIM].

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: LIMS2 Antibody (C-term) can be refrigerated at 2-8°,C for up to 6 months. For long term storage, place the at -20°,C.

Research Area: Phospho-specific antibodies, Cell Structure, Protein Modifications

Restrictions: For Research Use only

Images

LIMS2 Antibody (C-term) (ABIN657520) western blot analysis in mouse liver tissue lysates (35ug/lane). This demonstrates the LIMS2 antibody detected the LIMS2 protein (arrow).

Publications

Product: Tu, Huang, Zhang et al.: "A new focal adhesion protein that interacts with integrin-linked kinase and regulates cell adhesion and spreading." in: The Journal of cell biology, Vol. 153, Issue 3, pp. 585-98, 2001 (PubMed).

Zhang, Chen, Guo et al.: "Characterization of PINCH-2, a new focal adhesion protein that regulates the PINCH-1-ILK interaction, cell spreading, and migration." in: The Journal of biological chemistry, Vol. 277, Issue 41, pp. 38328-38, 2002 (PubMed).

Davila, Froeling, Tan et al.: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010 (PubMed).