Intercellular Adhesion Molecule 3 (ICAM3) (Center) antibody
| Antigen |
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| Synonyms |
CD50, CDW50, ICAM-R, TLN, Tlcn, Icam3, ICAM-3, MGC130520, ICAM3, FLJ12949 |
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Binding Site
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| Clonality |
Polyclonal |
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Host
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Reactivity
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Conjugate
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FITC (15), Biotin (11), PE (8), RPE (3), APC (2), PE-Dyomics 647 (2), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
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Application
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Flow Cytometry (FACS) (58), ELISA (28), Western Blotting (WB) (25), Immunofluorescence (IF) (23), Immunoprecipitation (IP) (21), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (16), Immunohistochemistry (IHC) (10), Functional Studies (Func) (6), Neutralization (Neut) (6), Immunohistochemistry (Fixed) (IHC (fx)) (5), Immunocytochemistry (ICC) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Blocking Antibody (Inhibition) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1), Intracellular Staining (IS) (1), To be determined by user (TBD) (1)
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| Catalog no. |
ABIN657631 |
| Quantity |
0.1 mg (0.25 mg/ml) |
| Price |
280.50 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Will be delivered in 2 to 3 Business Days |
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Alternative name
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ICAM3
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Gene ID
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3385
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UniProt
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NP_002153.2, P32942
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Immunogen
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This ICAM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-310 amino acids from the Central region of human ICAM3.
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Isotype
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Ig
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Description
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Other names: Intercellular adhesion molecule 3,ICAM3,
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Characteristics
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Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
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Specificity
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This ICAM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-310 amino acids from the Central region of human ICAM3.
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Molecular Weight
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59541 DA
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Comments
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Background: The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule.
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Application Notes
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The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500
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Concentration
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0.25 mg/ml
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Purification
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Purified
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Buffer
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Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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Storage
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ICAM3 Antibody (Center) can be refrigerated at 2-8°,C for up to 6 months. For long term storage, place the at -20°,C.
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Research Area
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Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications
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Restrictions
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For Research Use only
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Product
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Mosbruger, Duggal, Goedert et al.: "Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus." in: The Journal of infectious diseases, Vol. 201, Issue 9, pp. 1371-80, 2010 (PubMed).
Rajaraman, Brenner, Neta et al.: "Risk of meningioma and common variation in genes related to innate immunity." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 5, pp. 1356-61, 2010 (PubMed).
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Alternatives for antigen "Intercellular Adhesion Molecule 3 (ICAM3)", type "Antibodies"
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Hosts
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Mouse (70), Rabbit (35)
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Reactivities
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Human (108), Mouse (Murine) (2), Rat (Rattus) (2), Cat (Feline) (1), Chicken (1), Cow (Bovine) (1), Dog (Canine) (1)
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Applications
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Flow Cytometry (FACS) (58), ELISA (28), Western Blotting (WB) (25), Immunofluorescence (IF) (23), Immunoprecipitation (IP) (21), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (16), Immunohistochemistry (IHC) (10), Functional Studies (Func) (6), Neutralization (Neut) (6), Immunohistochemistry (Fixed) (IHC (fx)) (5), Immunocytochemistry (ICC) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Blocking Antibody (Inhibition) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1), Intracellular Staining (IS) (1), To be determined by user (TBD) (1)
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Conjugates
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FITC (15), Biotin (11), PE (8), RPE (3), APC (2), PE-Dyomics 647 (2), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), HRP (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
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Epitopes
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pSer518,C-Term (6), C-Term (1), Internal Region,AA 281-310 (1)
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Alternatives 
