rho GTPase Activating Protein 24 (ARHGAP24) (C-Term) antibody

Antigen: rho GTPase Activating Protein 24 (ARHGAP24)

Binding Site: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN657747

Additional Information

Alternative name: ARHGAP24

Gene ID: 83478

UniProt: NP_001020787.2, NP_112595.2, NP_001036134.1, Q8N264

Immunogen: This ARHGAP24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 586-616 amino acids from the C-terminal region of human ARHGAP24.

Isotype: Ig

Description: Other names: Rho GTPase-activating protein 24,ARHGAP24,FILGAP

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This ARHGAP24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 586-616 amino acids from the C-terminal region of human ARHGAP24.

Molecular Weight: 84258 DA

Comments:

Background: ARHGAPs, such as ARHGAP24, encode negative regulators of Rho GTPases (see ARHA, MIM 165390), which are implicated in actin remodeling, cell polarity, and cell migration (Katoh and Katoh, 2004 [PubMed 15254788]).

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: ARHGAP24 Antibody (C-term) can be refrigerated at 2-8°,C for up to 6 months. For long term storage, place the at -20°,C.

Research Area: Phospho-specific antibodies, Cell Structure, Protein Modifications, Cell Cycle

Restrictions: For Research Use only

Images

ARHGAP24 Antibody (C-term) (ABIN657747) western blot analysis in SK-BR-3 cell line lysates (35ug/lane). This demonstrates the ARHGAP24 antibody detected the ARHGAP24 protein (arrow).

Publications

Product: Pfeufer, van Noord, Marciante et al.: "Genome-wide association study of PR interval." in: Nature genetics, Vol. 42, Issue 2, pp. 153-9, 2010 (PubMed).

Holm, Gudbjartsson, Arnar et al.: "Several common variants modulate heart rate, PR interval and QRS duration." in: Nature genetics, Vol. 42, Issue 2, pp. 117-22, 2010 (PubMed).

Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Horinouchi, Yagi, Imanishi et al.: "Association of genetic polymorphisms with hepatotoxicity in patients with childhood acute lymphoblastic leukemia or lymphoma." in: Pediatric hematology and oncology, Vol. 27, Issue 5, pp. 344-54, 2010 (PubMed).