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Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2) (N-Term) antibody

Antigen

Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2)

Synonyms AG2, GOB-4, HAG-2, XAG-2, PDIA17, Agr2h, Gob-4, mAG-2, MGC112187, wu:fj29g05, zgc:112187, agr2, AGR2, MGC128276, hag3, hag-3, bcmp11, MGC89004
Binding Site
Alternatives

N-Term

Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Human

Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), ELISA
1 reference available
Certificates ISO 9001:2008
Catalog no. ABIN657766
Quantity 0.1 mg  (0.25 mg/ml)  (Variants)
Price 280.50 $   Plus shipping costs $45.00
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Additional Information

Alternative name AGR2
Gene ID 10551
UniProt O95994, NP_006399.1
Immunogen This AGR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-39 amino acids from the N-terminal region of human AGR2.
Isotype Ig
Description Other names: Anterior gradient protein 2 homolog,AGR2,AG2
Characteristics Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Specificity This AGR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-39 amino acids from the N-terminal region of human AGR2.
Molecular Weight 19979 DA
Comments

Background: Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth.

Application Details

Application Notes The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500
Concentration 0.25 mg/ml
Purification Purified
Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage AGR2 Antibody (N-term) can be refrigerated at 2-8°,C for up to 6 months. For long term storage, place the at -20°,C.
Research Area Cell Signaling, Protein Modifications, Cancer, Cell Structure
Restrictions For Research Use only

Publications

Product Vanderlaag, Hudak, Bald et al.: "Anterior gradient-2 plays a critical role in breast cancer cell growth and survival by modulating cyclin D1, estrogen receptor-alpha and survivin." in: Breast cancer research : BCR, Vol. 12, Issue 3, pp. R32, 2010 (PubMed).

Alternatives

Alternatives for antigen "Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2)", type "Antibodies"
Hosts Rabbit (35), Mouse (6), Goat (5), Sheep (1)
Reactivities Human (41), Mouse (Murine) (14), Rat (Rattus) (9), Cow (Bovine) (3), Dog (Canine) (3), Chicken (2), Cat (Feline) (1), Horse (Equine) (1), Monkey (1), Orang-Utan (1), Zebrafish (1)
Applications Western Blotting (WB) (40), ELISA (32), Immunohistochemistry (IHC) (20), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (15), Immunoprecipitation (IP) (4), Immunocytochemistry (ICC) (3), Flow Cytometry (FACS) (2), Immunofluorescence (IF) (2), Dot Blot (DB) (1), Immunohistochemistry (Fixed) (IHC (fx)) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
Conjugates Biotin (3)
Epitopes N-Term (6), AA 21-175 (3), AA 55-72 (3), Internal Region (3), AA 50-100 (1), Center (1), N-Term,AA 10-39 (1)