Tachykinin Receptor 1 (TACR1) (Center) antibody

Antigen: Tachykinin Receptor 1 (TACR1)

Synonyms: SPR, NK1R, NKIR, TAC1R, TACR1

Binding Site: Center

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN657820

Additional Information

Alternative name: TACR1

Gene ID: 6869

UniProt: P25103, NP_001049.1, NP_056542.1

Immunogen: This TACR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-248 amino acids from the Central region of human TACR1.

Isotype: Ig

Description: Other names: Substance-P receptor,TACR1,NK1R, TAC1R

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This TACR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-248 amino acids from the Central region of human TACR1.

Molecular Weight: 46251 DA

Comments:

Background: This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P. [provided by RefSeq].

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: TACR1 Antibody (Center) can be refrigerated at 2-8°,C for up to 6 months. For long term storage, place the at -20°,C.

Research Area: Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications

Restrictions: For Research Use only

Images

TACR1 Antibody (Center) (ABIN657820) western blot analysis in HL-60 cell line lysates (35ug/lane). This demonstrates the TACR1 antibody detected the TACR1 protein (arrow).

Publications

Product: Saus, Brunet, Armengol et al.: "Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients." in: Journal of psychiatric research, Vol. 44, Issue 14, pp. 971-8, 2010 (PubMed).