TACR1 antibody (2nd Extracellular Loop) (Atto 488)

Catalog No. ABIN7043804

Product Details anti-TACR1 Antibody (Atto 488)

Target: TACR1 (Tachykinin Receptor 1 (TACR1))

Binding Specificity: 2nd Extracellular Loop, AA 180-194

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TACR1 antibody is conjugated to Atto 488

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Characteristics: Anti-Neurokinin 1 Receptor (NK1R) (extracellular) Antibody (ABIN7043803, ABIN7045318 and ABIN7045319)) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot, indirect live cell flow cytometry, and live cell imaging applications. It has been designed to recognize NK1 receptor from rat, mouse, and human samples. \nAnti-Neurokinin 1 Receptor (NK1R) (extracellular)-ATTO Fluor-488 Antibody (#ABIN7043804) is directly labeled with an ATTO-488 fluorescent dye. ATTO dyes are characterized by strong absorption (high extinction coefficient), high fluorescence quantum yield, and high photo-stability. The ATTO-488 label is analogous to the well known dye fluorescein isothiocyanate (FITC) and can be used with filters typically used to detect FITC. Anti-Neurokinin 1 Receptor (NK1R) (extracellular)-ATTO Fluor-488 Antibody is especially suited for experiments requiring simultaneous labeling of different markers.

Purification: Affinity purified on immobilized antigen.

Immunogen:

Immunogen: Synthetic peptide

Immunogen Sequence: CMIEWPEHPNRTYEK, corresponding to amino acid residues 180-194 of rat NK1 receptor

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: 50 μL double distilled water (DDW).

Concentration: 1 mg/mL

Buffer: Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1 % BSA, 0.05 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: RT,4 °C,-20 °C

Storage Comment:

Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.

Storage after reconstitution: The reconstituted solution can be stored at 4°C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

Target Details for TACR1

Target: TACR1 (Tachykinin Receptor 1 (TACR1))

Alternative Name: Neurokinin 1 Receptor (NK1R) (TACR1 Products)

Synonyms: NK1R antibody, NKIR antibody, SPR antibody, TAC1R antibody, Nk1r antibody, Spr antibody, Tac1r antibody, nk1R antibody, Tacr1 antibody, ASPR antibody, tachykinin receptor 1 antibody, TACR1 antibody, Tacr1 antibody

Background: Alternative names: Neurokinin 1 Receptor (NK1R), NK1 receptor, Tachykinin receptor 1, TACR1, Substance-P receptor, SPR

Gene ID: 24807

NCBI Accession: NM_001058

UniProt: P14600

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration