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Chymotrypsin-Like Elastase Family, Member 2A (CELA2A) (C-Term) antibody
|Synonyms||Ela2, Ela-2, Ela2a, ELAII, Elaii1, PE-1, ELA2A, CELA2A, ela2, ela2a|
Western Blotting (WB), ELISA
|2 references available|
|Quantity||0.1 mg (0.25 mg/ml)|
|Price||280.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||This CELA2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-260 amino acids from the C-terminal region of human CELA2A.|
|Description||Other names: Chymotrypsin-like elastase family member 2A,63036,ELA2A|
|Characteristics||Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)|
|Specificity||This CELA2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-260 amino acids from the C-terminal region of human CELA2A.|
|Molecular Weight||28888 DA|
Background: Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Like most of the human elastases, elastase 2A is secreted from the pancreas as a zymogen. In other species, elastase 2A has been shown to preferentially cleave proteins after leucine, methionine, and phenylalanine residues.
|Application Notes||The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500|
|Buffer||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||CELA2A Antibody (C-term) can be refrigerated at 2-8°,C for up to 6 months. For long term storage, place the at -20°,C.|
|Research Area||Cell Signaling, Protein Modifications, Metabolism, Cell Structure|
|Restrictions||For Research Use only|
|CELA2A Antibody (C-term) (ABIN657926) western blot analysis in MDA-MB435 cell line lysates (35ug/lane). This demonstrates the CELA2A antibody detected the CELA2A protein (arrow).|
Lausen, Liu, Fliegauf et al.: "ELA2 is regulated by hematopoietic transcription factors, but not repressed by AML1-ETO." in: Oncogene, Vol. 25, Issue 9, pp. 1349-57, 2006 (PubMed).
Lamesch, Li, Milstein et al.: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, 2007 (PubMed).