Activin A Receptor Type IB/ALK-4 antibody

Catalog No. ABIN659054

The Mouse Monoclonal anti-Activin A Receptor Type IB/ALK-4 antibody is suitable to detect Activin A Receptor Type IB/ALK-4 in samples from Mouse. It has been validated for WB.

Quick Overview for Activin A Receptor Type IB/ALK-4 antibody (ABIN659054)

Target: Activin A Receptor Type IB/ALK-4 (ACVR1B) (Activin A Receptor, Type IB (ACVR1B))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Activin A Receptor Type IB/ALK-4 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 179CT11-2-1

Product Details anti-Activin A Receptor Type IB/ALK-4 Antibody

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This ACVR1B monoclonal antibody is generated from mouse immunized with ACVR1B recombinant protein.

Isotype: IgG1 kappa

Application Details

Application Notes: WB: 1:100~500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Activin A Receptor Type IB/ALK-4

Target: Activin A Receptor Type IB/ALK-4 (ACVR1B) (Activin A Receptor, Type IB (ACVR1B))

Alternative Name: ACVR1B

Background: This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.

Molecular Weight: 56807

Gene ID: 91

NCBI Accession: NP_004293, NP_064732, NP_064733

UniProt: P36896