Activin A Receptor Type IB/ALK-4 antibody (C-Term)

Catalog No. ABIN1099822

This Rabbit Polyclonal antibody specifically detects Activin A Receptor Type IB/ALK-4 in WB, IHC and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for Activin A Receptor Type IB/ALK-4 antibody (C-Term) (ABIN1099822)

Target: Activin A Receptor Type IB/ALK-4 (ACVR1B) (Activin A Receptor, Type IB (ACVR1B))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Activin A Receptor Type IB/ALK-4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Activin A Receptor Type IB/ALK-4 Antibody

Binding Specificity: C-Term

Specificity: At least three isoforms of ACVR1B are known to exist. This antibody is predicted to have no cross-reactivity to ACVR1 or ACVR1C.

Purification: Immunoaffinity purified

Isotype: IgG

Application Details

Application Notes: Approved: IHC, IHC-P (5 μg/mL), WB (1 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles. Store undiluted.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for 3 months and -20°C, stable for up to 1 year. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Activin A Receptor Type IB/ALK-4

Target: Activin A Receptor Type IB/ALK-4 (ACVR1B) (Activin A Receptor, Type IB (ACVR1B))

Alternative Name: ACVR1B / ALK4

Background: Name/Gene ID: ACVR1B
Subfamily: Activin/TGFb
Family: Protein Kinase

Synonyms: ACVR1B, ACTR-IB, ACTRIB, ALK4, Activin receptor type IB, Activin A Receptor Type IB, Activin A receptor, type IB, Activin receptor-like kinase 4, ACVRLK4, ALK-4, Activin receptor type-1B, SKR2-2, SKR2

Gene ID: 91

UniProt: Q04771