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Details for Product No. ABIN659178

ATG4 Autophagy Related 4 Homolog C (S. Cerevisiae) (ATG4C) antibody

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Antigen
Synonyms APG4-C, APG4C, AUTL1, AUTL3, Apg4-C, Apg4c, Atg4cl, Autl1, apg4c, atg4cl, zgc:86888, wu:fc56g07
Reactivity
»Alternatives Mouse (Murine)
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN659178
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This ATG4C monoclonal antibody is generated from mouse immunized with ATG4C recombinant protein.
Clone 287CT12-2-2
Isotype IgG1, kappa
Specificity This ATG4C monoclonal antibody is generated from mouse immunized with ATG4C recombinant protein.
Purification This antibody is purified through a protein G column, followed by dialysis against PBS.
Alternative Name ATG4C
Background Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized. [provided by RefSeq].
Synonyms: ATG4C,Cysteine protease ATG4C,APG4C, AUTL1, AUTL3
Molecular Weight 52497 DA
Gene ID 84938
UniProt NP_116241.2, Q96DT6, NP_835739.1
Research Area Signaling, Protein Modifications, Autophagy, Metabolism, Cell Structure
Application Notes Recommend dilutions: WB : 1:100
Restrictions For Research Use only
Format Liquid
Concentration 0.35 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment ATG4C Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Background publications Mariño, Salvador-Montoliu, Fueyo et al.: "Tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3." in: The Journal of biological chemistry, Vol. 282, Issue 25, pp. 18573-83, 2007 (PubMed).

Kathiresan, Melander, Guiducci et al.: "Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans." in: Nature genetics, Vol. 40, Issue 2, pp. 189-97, 2008 (PubMed).

Alternatives for antigen "ATG4 Autophagy Related 4 Homolog C (S. Cerevisiae) (ATG4C)", type "Antibodies"
Hosts (87), (4), (4), (1)
Reactivities (83), (72), (67), (48), (48), (48)
Applications (50), (44), (30), (18), (15), (10), (5), (3), (2), (1), (1)
Conjugates (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5)
Epitopes (12), (12), (12), (12), (3), (2), (2), (2), (2), (1), (1)
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