ATG4 Autophagy Related 4 Homolog C (S. Cerevisiae) (ATG4C) antibody

Details for Product No. ABIN659178
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Antigen
Synonyms apg4c, atg4cl, zgc:86888, wu:fc56g07, APG4-C, APG4C, AUTL1, AUTL3, Apg4-C, Apg4c, Atg4cl, Autl1
Reactivity
Mouse (Murine)
(71), (46), (22), (1)
Host
Mouse
(56), (20), (8), (3)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(4), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(75), (41), (31), (14), (10), (5), (3), (2), (2)
Pubmed 2 references available
Quantity 400 μL
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Immunogen This ATG4C monoclonal antibody is generated from mouse immunized with ATG4C recombinant protein.
Clone 287CT12-2-2
Isotype IgG1, kappa
Specificity This ATG4C monoclonal antibody is generated from mouse immunized with ATG4C recombinant protein.
Purification This antibody is purified through a protein G column, followed by dialysis against PBS.
Alternative Name ATG4C (ATG4C Antibody Abstract)
Background Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized. [provided by RefSeq].
Synonyms: ATG4C,Cysteine protease ATG4C,APG4C, AUTL1, AUTL3
Molecular Weight 52497 DA
Gene ID 84938
NCBI Accession NP_835739, NP_116241
UniProt Q96DT6
Research Area Signaling, Protein Modifications, Autophagy, Metabolism, Cell Structure
Application Notes WB = 1:100
Restrictions For Research Use only
Format Liquid
Concentration 0.35 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment ATG4C Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-ATG4 Autophagy Related 4 Homolog C (S. Cerevisiae) (ATG4C) antibody ATG4C Antibody western blot analysis in mouse heart tissue lysates (35ug/lane).This ...
Background publications Kathiresan, Melander, Guiducci et al.: "Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. ..." in: Nature genetics, Vol. 40, Issue 2, pp. 189-97, 2008 (PubMed).

Mariño, Salvador-Montoliu, Fueyo et al.: "Tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3." in: The Journal of biological chemistry, Vol. 282, Issue 25, pp. 18573-83, 2007 (PubMed).

Validation Images
Catalog No. ABIN659178
291.50 $
Plus shipping costs $45.00
Quantity
Price
400 μL
291.50 $

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