PIWIL1 antibody (AA 551-650)

Catalog No. ABIN671631

Cited in 1 publication. The Rabbit Polyclonal anti-PIWIL1 antibody (ABIN671631) specifically detects PIWIL1 in WB, IF (cc), IF (p), IHC (p) and IHC (fro). The antibody is reactive with Chicken samples.

Quick Overview for PIWIL1 antibody (AA 551-650) (ABIN671631)

Target: PIWIL1 (Piwi-Like 1 (PIWIL1))

Reactivity: Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIWIL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-PIWIL1 Antibody

Binding Specificity: AA 551-650

Purpose: PIWIL1 Polyclonal Antibody

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from chicken PIWIL1

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-PIWIL1 antibody (ABIN671631)

Liu, Jiang, Zhang: "Expression of PSCA, PIWIL1 and TBX2 and its correlation with HPV16 infection in formalin-fixed, paraffin-embedded cervical squamous cell carcinoma specimens." in: Archives of virology, Vol. 155, Issue 5, pp. 657-63, (2010) (PubMed).

Target Details for PIWIL1

Target: PIWIL1 (Piwi-Like 1 (PIWIL1))

Alternative Name: PIWIL1

Background:

Synonyms: PIWI, Piwi-like protein 1, PIWIL1

Background: Plays a central role during gametogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds methylated piRNAs, a class of 24 to 3 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Besides their function in transposable elements repression, piRNAs are probably involved in other processes during meiosis such as translation regulation (By similarity).

Gene ID: 416804

UniProt: A6N7Y9