Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1) antibody

Antigen: Eukaryotic Translation Initiation Factor 4 Gamma, 1 (EIF4G1)

Synonyms: p220, EIF4F, EIF4G, DKFZp686A1451, Eif4G, deIF4G, eIF-4G, p200, DmelCG10811, CG10811, EIF4GI, EIF4G1, MGC158450, wu:fb50a05, wu:fc60b06, CH73-211A15.2, eif4g, CUCUMOVIRUS MULTIPLICATION 2, CUM2, EUKARYOTIC TRANSLATION INITIATION FACTOR 4G, NV18824

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Rat (Rattus), Mouse (Murine)

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Flow Cytometry (FACS), Immunofluorescence (IF)

Catalog no.: ABIN704936

Additional Information

Alternative name: eIF4G

Immunogen: Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human eIF4G C-terminus

Format: Lyophilized

Reconstitution: Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%)

Isotype: IgG  (Matching secondary antibodies)

Description: Synonym: eIF 4 gamma 1, eIF 4G 1, eIF 4G1, eIF4G1, EIF4 gamma, EIF4F, EIF4G, EIF4GI, Eukaryotic translation initiation factor 4 gamma 1, p220, DKFZp686A1451.

Molecular Weight: 200-220kDa

Comments:

The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome

which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein

which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants

some of which are derived from alternative promoter usage.

Synonyms: p220, EIF4F, EIF4G, DKFZp686A1451, Eif4G, deIF4G, eIF-4G, p200, DmelCG10811, CG10811, EIF4GI, EIF4G1, MGC158450, wu:fb50a05, wu:fc60b06, CH73-211A15.2, eif4g, CUCUMOVIRUS MULTIPLICATION 2, CUM2, EUKARYOTIC TRANSLATION INITIATION FACTOR 4G, NV18824

Application Details

Application Notes: WB (1:100-500), ELISA (1:500-1000), IP (1:20-100), IHC-P (1:100-500), IHC-F (1:100-500), Flow-Cyt (1:20-100), IF (1:50-200)

Concentration: 1mg/1ml

Purification: affinity purified by Protein A

Buffer: 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

Storage: Ship at room temperature. Store at -20°C

Restrictions: For Research Use only