SCNN1G antibody (AA 220-270) (Cy3)

Catalog No. ABIN706079

The Rabbit Polyclonal anti-SCNN1G antibody is suitable to detect SCNN1G in samples from Human, Rat and Mouse. It has been validated for IF (p).

Quick Overview for SCNN1G antibody (AA 220-270) (Cy3) (ABIN706079)

Target: SCNN1G (Sodium Channel, Nonvoltage-Gated 1, gamma (SCNN1G))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCNN1G antibody is conjugated to Cy3

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-SCNN1G Antibody (Cy3)

Binding Specificity: AA 220-270

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ENaCg

Isotype: IgG

Application Details

Application Notes: IF(IHC-P)(1:50-200)

Comment:

Exitation/Emission: 512,550nm/570,615nm

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at 4°C

Expiry Date: 12 months

Target Details for SCNN1G

Target: SCNN1G (Sodium Channel, Nonvoltage-Gated 1, gamma (SCNN1G))

Alternative Name: Enacg

Background:

Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.

Subcellular location: Extracellular

Synonyms: PHA1, BESC3, ENaCg, SCNEG, ENaCgamma, Amiloride-sensitive sodium channel subunit gamma, Epithelial Na(+) channel subunit gamma, Gamma-ENaC, Gamma-NaCH, Nonvoltage-gated sodium channel 1 subunit gamma, SCNN1G

Gene ID: 6340

UniProt: P51170