SCNN1B antibody (pThr615) (PE-Cy5)

Catalog No. ABIN713468

The Rabbit Polyclonal anti-SCNN1B antibody is suitable to detect SCNN1B in samples from Human, Mouse, Rat, Dog, Cow and Guinea Pig. It has been validated for WB.

Quick Overview for SCNN1B antibody (pThr615) (PE-Cy5) (ABIN713468)

Target: SCNN1B (Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCNN1B antibody is conjugated to PE-Cy5

Application: Western Blotting (WB)

Product Details anti-SCNN1B Antibody (PE-Cy5)

Binding Specificity: pThr615

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human SCNN1B around the phosphorylation site of Thr615

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SCNN1B

Target: SCNN1B (Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B))

Alternative Name: SCNN1B

Background:

Synonyms: BESC1, ENaCb, SCNEB, ENaCbeta, Amiloride-sensitive sodium channel subunit beta, Beta-NaCH, Epithelial Na(+) channel subunit beta, Beta-ENaC, Nonvoltage-gated sodium channel 1 subunit beta, SCNN1B

Background: Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.

Molecular Weight: 73kDa

Gene ID: 6338

UniProt: P51168