ID3 antibody (AA 25-119) (Cy7)

Catalog No. ABIN716072

The Rabbit Polyclonal anti-ID3 antibody is suitable to detect ID3 in samples from Human. It has been validated for IF (cc) and IF (p).

Quick Overview for ID3 antibody (AA 25-119) (Cy7) (ABIN716072)

Target: ID3 (Inhibitor of DNA Binding 3, Dominant Negative Helix-Loop-Helix Protein (ID3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ID3 antibody is conjugated to Cy7

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-ID3 Antibody (Cy7)

Binding Specificity: AA 25-119

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ID3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ID3

Target: ID3 (Inhibitor of DNA Binding 3, Dominant Negative Helix-Loop-Helix Protein (ID3))

Alternative Name: ID3

Background:

Synonyms: 1R21, bHLHb25, Class B basic helix-loop-helix protein 25, DNA binding protein inhibitor ID 3, DNA-binding protein inhibitor ID-3, HEIR 1, HEIR1, Helix loop helix protein HEIR 1, Helix loop helix protein HEIR1, Helix-loop-helix protein HEIR-1, HLH642, ID 3, ID like protein inhibitor HLH 1R21, ID like protein inhibitor HLH 462, ID-like protein inhibitor HLH 1R21, ID3, ID3_HUMAN, Inhibitor of DNA binding 3, Inhibitor of DNA binding 3 dominant negative helix loop helix protein.

Background: ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. ID-3 inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. May inhibit other transcription factors.

Gene ID: 3399