ID3 antibody (AA 27-99)

Catalog No. ABIN7150372

Product Details anti-ID3 Antibody

Target: ID3 (Inhibitor of DNA Binding 3, Dominant Negative Helix-Loop-Helix Protein (ID3))

Binding Specificity: AA 27-99

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ID3 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human DNA-binding protein inhibitor ID-3 protein (27-99AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ID3

Target: ID3 (Inhibitor of DNA Binding 3, Dominant Negative Helix-Loop-Helix Protein (ID3))

Alternative Name: ID3 (ID3 Products)

Synonyms: HEIR-1 antibody, bHLHb25 antibody, Hlh462 antibody, Idb3 antibody, fa56g03 antibody, tdsubc_2g3 antibody, wu:fa56g03 antibody, ik:tdsubc_2g3 antibody, xx:tdsubc_2g3 antibody, XId3 antibody, XIdI antibody, XIdIa antibody, XIdIb antibody, XIdx antibody, heir-1 antibody, id3 antibody, xid3 antibody, xidia antibody, ID3 antibody, XIdIIa antibody, inhibitor of DNA binding 3, HLH protein antibody, inhibitor of DNA binding 3 antibody, inhibitor of DNA binding 3, HLH protein L homeolog antibody, inhibitor of DNA binding 3, HLH protein S homeolog antibody, ID3 antibody, Id3 antibody, id3 antibody, id3.L antibody, id3.S antibody

Background:

Background: Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Involved in myogenesis by inhibiting skeletal muscle and cardiac myocyte differentiation and promoting muscle precursor cells proliferation. Inhibits the binding of E2A-containing protein complexes to muscle creatine kinase E-box enhancer. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer.

Aliases: 1R21 antibody, bHLHb25 antibody, Class B basic helix-loop-helix protein 25 antibody, DNA binding protein inhibitor ID 3 antibody, DNA-binding protein inhibitor ID-3 antibody, HEIR 1 antibody, HEIR1 antibody, Helix loop helix protein HEIR 1 antibody, Helix loop helix protein HEIR1 antibody, Helix-loop-helix protein HEIR-1 antibody, HLH642 antibody, ID 3 antibody, ID like protein inhibitor HLH 1R21 antibody, ID like protein inhibitor HLH 462 antibody, ID-like protein inhibitor HLH 1R21 antibody, ID3 antibody, ID3_HUMAN antibody, Inhibitor of DNA binding 3 antibody, Inhibitor of DNA binding 3 dominant negative helix loop helix protein antibody

UniProt: Q02535