UACA (UACA) antibody
| Antigen |
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| Synonyms |
NUCLING, FLJ10128, KIAA1561, MGC141967, MGC141969 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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 Alternatives Human, Mouse (Murine), Rat (Rattus), Cow (Bovine), Horse (Equine), Rabbit
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Application
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Alternatives Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Flow Cytometry (FACS), Immunofluorescence (IF)
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| Catalog no. |
ABIN717191 |
| Quantity |
100 µg (1mg/1ml) |
| Price |
255.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 5 to 7 Business Days |
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Alternative name
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UACA
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Immunogen
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Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human UACA
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Format
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Lyophilized
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Reconstitution
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Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%)
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Isotype
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IgG (Matching secondary antibodies)
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Description
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Synonym: Uaca, Kiaa1561, Conflict, Uveal autoantigen with coiled coil domains and ankyrin repeats, Uveal autoantigen with coiled-coil domains and ankyrin repeats, Nuclear membrane-binding protein, Nucling.
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Molecular Weight
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156kDa
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Comments
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Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways apoptosome up-regulation LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation.Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1.Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility.Interaction with ARF6 may modulate cell shape and motility after injury (By similarity).
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Application Notes
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WB (1:100-500), ELISA (1:500-1000), IP (1:20-100), IHC-P (1:100-500), IHC-F (1:100-500), Flow-Cyt (1:20-100), IF (1:50-200)
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Concentration
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1mg/1ml
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Purification
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affinity purified by Protein A
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Buffer
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Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
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Storage
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Ship at room temperature. Store at -20°C
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Restrictions
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For Research Use only
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Alternatives for antigen "UACA (UACA)", type "Antibodies"
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Hosts
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Rabbit (19), Mouse (1)
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Reactivities
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Human (20), Cow (Bovine) (14), Horse (Equine) (14), Mouse (Murine) (14), Rabbit (14), Rat (Rattus) (14)
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Applications
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Flow Cytometry (FACS) (17), Immunofluorescence (IF) (17), Western Blotting (WB) (3), ELISA (2), ELISA (Detection) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (1), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (1), Immunoprecipitation (IP) (1)
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Conjugates
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Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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