UACA (UACA) antibody (Cy7)
| Antigen |
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| Synonyms |
NUCLING, FLJ10128, KIAA1561, MGC141967, MGC141969 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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 Alternatives Human, Mouse (Murine), Rat (Rattus), Cow (Bovine), Horse (Equine), Rabbit
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Conjugate
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Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Application
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| Catalog no. |
ABIN717197 |
| Quantity |
100 µg (1mg/1ml) |
| Price |
330.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 10 to 15 Business Days |
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Alternative name
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UACA
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Immunogen
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Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human UACA
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Format
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Lyophilized
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Reconstitution
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Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%)
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Isotype
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IgG
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Description
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Synonym: Uaca, Kiaa1561, Conflict, Uveal autoantigen with coiled coil domains and ankyrin repeats, Uveal autoantigen with coiled-coil domains and ankyrin repeats, Nuclear membrane-binding protein, Nucling.
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Specificity
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Excitation / Emission Wavelengths: 743nm/767nm
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Molecular Weight
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156kDa
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Comments
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Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways apoptosome up-regulation LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation.Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1.Modulates isoactin dynamics to regulate the morphological alterations required for cell growth and motility.Interaction with ARF6 may modulate cell shape and motility after injury (By similarity).
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Application Notes
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Flow-Cyt (1:50-200), IF (1:50-200)
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Concentration
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1mg/1ml
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Purification
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Antibodies are purified by protein A and peptide affinity chromatography.
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Buffer
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Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
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Storage
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Ship at room temperature. Store at -20°C
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Restrictions
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For Research Use only
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Alternatives for antigen "UACA (UACA)", type "Antibodies"
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Hosts
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Rabbit (19), Mouse (1)
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Reactivities
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Human (20), Cow (Bovine) (14), Horse (Equine) (14), Mouse (Murine) (14), Rabbit (14), Rat (Rattus) (14)
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Applications
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Flow Cytometry (FACS) (17), Immunofluorescence (IF) (17), Western Blotting (WB) (4), ELISA (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2), Immunoprecipitation (IP) (2), ELISA (Detection) (1), Immunoelectron Microscopy (IEM) (1)
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Conjugates
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Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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