SCN1B antibody (AA 21-120) (Cy5.5)

Catalog No. ABIN719971

This Rabbit Polyclonal antibody specifically detects SCN1B in IF (cc) and IF (p). It exhibits reactivity toward Human.

Quick Overview for SCN1B antibody (AA 21-120) (Cy5.5) (ABIN719971)

Target: SCN1B (Sodium Channel, Voltage-Gated, Type I, beta (SCN1B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCN1B antibody is conjugated to Cy5.5

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-SCN1B Antibody (Cy5.5)

Binding Specificity: AA 21-120

Predicted Reactivity: Human,Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SCN1B

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SCN1B

Target: SCN1B (Sodium Channel, Voltage-Gated, Type I, beta (SCN1B))

Alternative Name: SCN1B

Background:

Synonyms: GEFSP1, SCN1B, SCN1B_HUMAN, sodium channel beta 1 subunit, Sodium channel subunit beta 1, Sodium channel subunit beta-1, Sodium channel voltage gated type I beta.

Background: Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-1 can modulate multiple alpha subunit isoforms from brain, skeletal muscle, and heart. Its association with neurofascin may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.Tissue specificity, Abundantly expressed in skeletal muscle, heart and brain.

Gene ID: 6324