DFFA antibody (AA 2-100) (Cy5)

Catalog No. ABIN726384

The Cy5-conjugated Rabbit Polyclonal anti-DFFA antibody (ABIN726384) specifically detects DFFA in WB, IF (p) and IF (cc). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for DFFA antibody (AA 2-100) (Cy5) (ABIN726384)

Target: DFFA (DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DFFA antibody is conjugated to Cy5

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Product Details anti-DFFA Antibody (Cy5)

Binding Specificity: AA 2-100

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse ICAD

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DFFA

Target: DFFA (DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA))

Alternative Name: ICAD

Background:

Synonyms: ICAD, DFF35, Dff45, ICAD-L, ICAD-S, A330085O09Rik, DNA fragmentation factor subunit alpha, DNA fragmentation factor 45 kDa subunit, DFF-45, Inhibitor of CAD, Dffa

Background: Inhibitor of the caspase-activated DNase (DFF40).

Gene ID: 13347

UniProt: O54786

Pathways: Apoptosis, Caspase Cascade in Apoptosis