GLUT2 antibody

Antigen: GLUT2

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse (Murine), Rat (Rattus), Cow (Bovine), Sheep (Ovine), Pig (Porcine), Dog (Canine), Chicken

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Flow Cytometry (FACS), Immunofluorescence (IF)

Catalog no.: ABIN739124

Additional Information

Immunogen: Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human GLUT2 C-terminus

Format: Lyophilized

Reconstitution: Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%)

Isotype: IgG  (Matching secondary antibodies)

Description: Synonym: liver, Glucose Transporter 2, Glucose Transporter GLUT2, Glucose transporter type 2, Glucose transporter type 2 liver, GLUT-2, GLUT2, GLUT 2, GTR2_HUMAN, SLC2A2, Solute carrier family 2 (facilitated glucose transporter) member 2, Solute carrier family 2 facilitated glucose transporter member 2, Solute carrier family 2, facilitated glucose transporter member 2.

Molecular Weight: 54kDa

Comments:

Glucose transporter 2 isoform is an integral plasma membrane glycoprotein of the liver

islet beta cells

intestine

and kidney epithelium. It mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose

it has been suggested as a glucose sensor. [provided by RefSeq

Jul 2008]. Facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells

may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney.

Application Details

Application Notes: WB (1:100-500), ELISA (1:500-1000), IP (1:20-100), IHC-P (1:100-500), IHC-F (1:100-500), Flow-Cyt (1:20-100), IF (1:50-200)

Concentration: 1mg/1ml

Purification: affinity purified by Protein A

Buffer: 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

Storage: Ship at room temperature. Store at -20°C

Restrictions: For Research Use only