SLC2A2 antibody (AA 482-524)

Catalog No. ABIN739124

There are 4+ publications for this product available. The Rabbit Polyclonal anti-SLC2A2 antibody is suitable to detect SLC2A2 in samples from Human, Rat and Mouse. It has been validated for WB, ELISA, FACS, IF (cc), IF (p), IHC (p) and IHC (fro).

Quick Overview for SLC2A2 antibody (AA 482-524) (ABIN739124)

Target: SLC2A2 (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC2A2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-SLC2A2 Antibody

Binding Specificity: AA 482-524

Cross-Reactivity: Goat, Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GLUT2

Isotype: IgG

Application Details

Application Notes: WB 1:100-1000
FCM 1:20-100
IHC-P 1:100-500
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-SLC2A2 antibody (ABIN739124)

Wang, Li, Guo, Li, Ren, Li: "Fibroblast growth factor 21 improves glucose homeostasis partially via down-regulation of Na+-d-glucose cotransporter SGLT1 in the small intestine." in: Biomedicine & pharmacotherapy, Vol. 109, pp. 1070-1077, (2019) (PubMed).

Zheng, Zhai, Li, Ma, Zhu, Du, Li, Hua: "The Modification of Tet1 in Male Germline Stem Cells and Interact with PCNA, HDAC1 to promote their Self-renewal and Proliferation." in: Scientific reports, Vol. 6, pp. 37414, (2016) (PubMed).

Klinger, Schröder, Gemmer, Reimers, Breves, Herrmann, Wilkens: "Gastrointestinal transport of calcium and glucose in lactating ewes." in: Physiological reports, Vol. 4, Issue 11, (2016) (PubMed).

Guttman, Yossef, Freixo-Lima, Rider, Porgador, Lewis: "?1-Antitrypsin modifies general NK cell interactions with dendritic cells and specific interactions with islet ?-cells in favor of protection from autoimmune diabetes." in: Immunology, (2014) (PubMed).

Target Details for SLC2A2

Target: SLC2A2 (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2))

Alternative Name: GLUT2

Background:

Synonyms: GLUT2, Solute carrier family 2, facilitated glucose transporter member 2, Glucose transporter type 2, liver, GLUT-2, SLC2A2

Background: Facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells, may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney.

Gene ID: 6514

UniProt: P11168

Pathways: Warburg Effect