PTGES2 antibody (AA 281-384) (HRP)

Catalog No. ABIN748412

The Rabbit Polyclonal anti-PTGES2 antibody is suitable to detect PTGES2 in samples from Human, Mouse and Rat. It has been validated for ELISA, IHC (p) and IHC (fro).

Quick Overview for PTGES2 antibody (AA 281-384) (HRP) (ABIN748412)

Target: PTGES2 (Prostaglandin E Synthase 2 (PTGES2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTGES2 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-PTGES2 Antibody (HRP)

Binding Specificity: AA 281-384

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse PGES2

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PTGES2

Target: PTGES2 (Prostaglandin E Synthase 2 (PTGES2))

Alternative Name: PGES2

Background:

Synonyms: Gbf1, Pges2, C79137, Mpges2, 6138H1Rik, Prostaglandin E synthase 2, GATE-binding factor 1, GBF-1, Microsomal prostaglandin E synthase 2, mPGES-2, Ptges2,

Background: Isomerase that catalyzes the conversion of PGH2 into the more stable prostaglandin E2 (PGE2) (By similarity). May also have transactivation activity toward IFN-gamma (IFNG), possibly via an interaction with CEBPB, however, the relevance of transcription activation activity remains unclear.

Gene ID: 96979

UniProt: Q8BWM0

Pathways: Interferon-gamma Pathway, Cell RedoxHomeostasis, SARS-CoV-2 Protein Interactome