SLC9A3R1 antibody (AA 281-358)

Catalog No. ABIN759296

The Rabbit Polyclonal anti-SLC9A3R1 antibody is suitable to detect SLC9A3R1 in samples from Human. It has been validated for WB, ELISA, IHC (p), IF (cc), IF (p) and IHC (fro).

Quick Overview for SLC9A3R1 antibody (AA 281-358) (ABIN759296)

Target: SLC9A3R1 (Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC9A3R1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-SLC9A3R1 Antibody

Binding Specificity: AA 281-358

Predicted Reactivity: Human,Mouse,Rat,Cow,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EBP50/SLC9A3R1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for SLC9A3R1

Target: SLC9A3R1 (Solute Carrier Family 9, Subfamily A (NHE3, Cation Proton Antiporter 3), Member 3 Regulator 1 (SLC9A3R1))

Alternative Name: EBP50

Background:

Synonyms: EBP 50, EBP50, Ezrin radixin moesin binding phosphoprotein 50, Ezrin-radixin-moesin-binding phosphoprotein 50, Na+/H+ exchange regulatory cofactor NHE RF, Na+/H+ exchange regulatory cofactor NHE-RF1, Na+/H+ exchange regulatory co factor, NHERF 1, NHERF, NHERF-1, NHERF1, NHRF1_HUMAN, NPHLOP2, Regulatory cofactor of Na+/H+ exchanger, SLC9A3R1, Sodium hydrogen exchanger regulatory factor 1, Sodium-hydrogen exchanger regulatory factor 1, Sodium/hydrogen exchanger regulatory factor 1, Solute carrier family 9 sodium/hydrogen exchanger member 3 regulator 1, Solute carrier family 9 sodium/hydrogen exchanger, isoform 3 regulatory factor 1, Solute carrier family 9 isoform 3 regulatory factor 1, Solute carrier family 9 isoform A3 regulatory factor 1, Solute carrier family 9 member 3 regulator 1.

Background: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for recycling of internalized ADRB2. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May enhance Wnt signaling. May participate in HTR4 targeting to microvilli (By similarity). Interacts with MCC.

Gene ID: 9368

Pathways: Proton Transport, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, SARS-CoV-2 Protein Interactome