HPGD antibody (AA 55-160)

Catalog No. ABIN761711

There are 2+ publications for this product available. The Rabbit Polyclonal anti-HPGD antibody is suitable to detect HPGD in samples from Human and Rat. It has been validated for WB, ELISA, IHC (p), IF (cc), IF (p) and IHC (fro).

Quick Overview for HPGD antibody (AA 55-160) (ABIN761711)

Target: HPGD (Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HPGD antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-HPGD Antibody

Binding Specificity: AA 55-160

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Prostaglandin dehydrogenase 1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-HPGD antibody (ABIN761711)

Hu, Li, Maskey, Xu, Peng, Tian, Li, Yang: "15-PGDH expression as a predictive factor response to neoadjuvant chemotherapy in advanced gastric cancer." in: International journal of clinical and experimental pathology, Vol. 8, Issue 6, pp. 6910-8, (2015) (PubMed).

Wei, Yu, Shi, Zhang, Lian, Li, Shen, Xing, Zhu: "15-PGDH/15-KETE plays a role in hypoxia-induced pulmonary vascular remodeling through ERK1/2-dependent PAR-2 pathway." in: Cellular signalling, Vol. 26, Issue 7, pp. 1476-1488, (2014) (PubMed).

Target Details for HPGD

Target: HPGD (Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD))

Alternative Name: Prostaglandin Dehydrogenase 1

Background:

Synonyms: PGDH, PGDH1, PHOAR1, 15-PGDH, SDR36C1, 15-hydroxyprostaglandin dehydrogenase [NAD(+)], Prostaglandin dehydrogenase 1, HPGD

Background: Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. Inhibits in vivo proliferation of colon cancer cells.

Gene ID: 3248

UniProt: P15428