HPGD antibody (AA 1-266)

Catalog No. ABIN6141966

Product Details anti-HPGD Antibody

Target: HPGD (Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD))

Binding Specificity: AA 1-266

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HPGD antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MHVNGKVALV TGAAQGIGRA FAEALLLKGA KVALVDWNLE AGVQCKAALD EQFEPQKTLF IQCDVADQQQ LRDTFRKVVD HFGRLDILVN NAGVNNEKNW EKTLQINLVS VISGTYLGLD YMSKQNGGEG GIIINMSSLA GLMPVAQQPV YCASKHGIVG FTRSAALAAN LMNSGVRLNA ICPGFVNTAI LESIEKEENM GQYIEYKDHI KDMIKYYGIL DPPLIANGLI TLIEDDALNG AIMKITTSKG IHFQDYDTTP FQAKTQ

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-266 of human 15-PGDH/15-PGDH/HPGD (NP_000851.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-HPGD antibody (ABIN6141966)

Wu, Liu, Yang, Liu, Liu, Wang, Xiong, Yu, Huang, Zhuang: "Association of 15-hydroxyprostaglandin dehydrogenate and poor prognosis of obese breast cancer patients." in: Oncotarget, Vol. 8, Issue 14, pp. 22842-22853, (2017) (PubMed).

Target Details for HPGD

Target: HPGD (Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD))

Alternative Name: HPGD (HPGD Products)

Synonyms: CBR antibody, SDR21C1 antibody, hCBR1 antibody, 15-PGDH antibody, PGDH antibody, PGDH1 antibody, PHOAR1 antibody, SDR36C1 antibody, MGC80546 antibody, MGC79454 antibody, AV026552 antibody, carbonyl reductase 1 antibody, 15-hydroxyprostaglandin dehydrogenase antibody, hydroxyprostaglandin dehydrogenase 15-(NAD) antibody, 15-hydroxyprostaglandin dehydrogenase L homeolog antibody, hydroxyprostaglandin dehydrogenase 15 (NAD) antibody, CBR1 antibody, HPGD antibody, hpgd.L antibody, hpgd antibody, pgdh antibody, Hpgd antibody, PTRG_03214 antibody, VDBG_09957 antibody

Background: This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene.,HPGD,15-PGDH,PGDH,PGDH1,PHOAR1,SDR36C1,Signal Transduction,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,HPGD

Molecular Weight: 15 kDa/19 kDa/21 kDa/28 kDa

Gene ID: 3248

UniProt: P15428