MCC antibody (AA 901-1019) (HRP)

Catalog No. ABIN762020

The Rabbit Polyclonal anti-MCC antibody is suitable to detect MCC in samples from Human. It has been validated for WB, ELISA, IHC (p) and IHC (fro).

Quick Overview for MCC antibody (AA 901-1019) (HRP) (ABIN762020)

Target: MCC (Mutated in Colorectal Cancers (MCC))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCC antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MCC Antibody (HRP)

Binding Specificity: AA 901-1019

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MCC

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MCC

Target: MCC (Mutated in Colorectal Cancers (MCC))

Alternative Name: MCC

Background:

Synonyms: Colorectal mutant cancer protein, MCC 1, MCC-1, MCC1, Mutated in colorectal cancers, Protein MCC, CRCM_HUMAN.

Background: This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Gene ID: 4163

UniProt: P23508