PHAP antibody (AA 41-140) (Biotin)

Catalog No. ABIN762178

This Rabbit Polyclonal antibody specifically detects PHAP in WB, ELISA, IHC (p), IHC (fro) and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PHAP antibody (AA 41-140) (Biotin) (ABIN762178)

Target: PHAP (ANP32A/ANP32B) (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A/B (ANP32A/ANP32B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHAP antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)

Product Details anti-PHAP Antibody (Biotin)

Binding Specificity: AA 41-140

Specificity: Will recognize Acidic leucine-rich nuclear phosphoprotein 32 family member C,D, and E

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PHAP1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500
IP(1-2 μg)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for PHAP

Target: PHAP (ANP32A/ANP32B) (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A/B (ANP32A/ANP32B))

Alternative Name: PHAP

Background:

Synonyms: Acidic leucine-rich nuclear phosphoprotein 32 family member A, Acidic nuclear phosphoprotein pp32, pp32, Leucine-rich acidic nuclear protein, LANP, Mapmodulin, Potent heat-stable protein phosphatase 2A inhibitor I1PP2A, Putative HLA-DR-associated protein I, PHAPI, ANP32A, C15orf1, MAPM, PHAP1

Background: Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase-independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. Plays a role in E4F1-mediated transcriptional repression.

Gene ID: 8125

UniProt: P39687