TNFRSF1B antibody (Internal Region)

Catalog No. ABIN768585

The Goat Polyclonal anti-TNFRSF1B antibody (ABIN768585) specifically detects TNFRSF1B in WB, IHC and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TNFRSF1B antibody (Internal Region) (ABIN768585)

Target: TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))

Reactivity: Human, Mouse, Rat

Host: Goat

Clonality: Polyclonal

Conjugate: This TNFRSF1B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Grade: Verified

Product Details anti-TNFRSF1B Antibody

Binding Specificity: Internal Region

Purpose: TNF-R-II / TNFR2 (mouse)

Sequence: KHFCNKTSDT VCAD

Specificity: The immunizing peptide represents part of a potential extracellular domain.

Cross-Reactivity: Mouse, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence KHFCNKTSDTVCAD, from the internal region of the protein sequence according to NP_035740.2.

Isotype: IgG

Application Details

Application Notes:

Immunohistochemistry: Paraffin embedded Human Liver. Recommended concentration: 5 μg/mL.

Western Blot: Approx 55 kDa band observed in Mouse and Rat Spinal Cord lysates (calculated MW of 50.3 kDa according to Mouse NP_035740.2). Recommended concentration: 0.2-0.6 μg/mL.

Peptide ELISA: antibody detection limit dilution 1:8000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for TNFRSF1B

Target: TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))

Alternative Name: Tnfrsf1b

Background: Tnfrsf1b, tumor necrosis factor receptor superfamily, member 1B, CD120b, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80, p75, p75TNFR, TNF-R2, TNF-RII, TNFR-II, p75 TNF receptor, p80 TNF-alpha receptor, soluble TNFR1B variant 1, tumor necrosis fac

Molecular Weight: 50.3kDa according to Mouse NP_035740.2

Gene ID: 21938, 156767

NCBI Accession: NP_035740

Pathways: NF-kappaB Signaling, Apoptosis, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Ubiquitin Proteasome Pathway