CD4 antibody

Catalog No. ABIN781715

The Mouse Monoclonal anti-CD4 antibody has been validated for FACS and IHC (fro). It is suitable to detect CD4 in samples from Human. There are 3+ publications available.

Quick Overview for CD4 antibody (ABIN781715)

Target: CD4

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD4 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: EDU-2

Product Details anti-CD4 Antibody

Specificity: This antibody detects CD4.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Affinity chromatography

Immunogen: Stimulated human leukocytes

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Stock solution contains 0.2 mg/mL IgG, phosphate buffered saline pH 7.2 (PBS), 5 mg/mL bovine serum albumin (BSA), and 0.09 % sodium azide as a preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.

References for anti-CD4 antibody (ABIN781715)

Borrego, Rodríguez-Pulido, Revilla, Álvarez, Sobrino, Domínguez, Sáiz: "Synthetic RNAs Mimicking Structural Domains in the Foot-and-Mouth Disease Virus Genome Elicit a Broad Innate Immune Response in Porcine Cells Triggered by RIG-I and TLR Activation." in: Viruses, Vol. 7, Issue 7, pp. 3954-73, (2016) (PubMed).

García, Quiroga, Ochoa, Ochoa, Pasquinelli, Fainboim, Olivares, Valdez, Sordelli, Aversa, Modlin, Sieling: "Signaling lymphocytic activation molecule expression and regulation in human intracellular infection correlate with Th1 cytokine patterns." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 10, pp. 5719-24, (2001) (PubMed).

Hogg, Whiley, De Soet: "Occurrence of lipoteichoic acid in oral streptococci." in: International journal of systematic bacteriology, Vol. 47, Issue 1, pp. 62-6, (1997) (PubMed).

Target Details for CD4

Target: CD4

Alternative Name: CD4

Background: CD4 is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells. It is mainly expressed by the T lymphocyte subset that recognizes antigens associated with self MHC class II molecules. CD4 is the primary receptor for HIV retroviruses. Like many cell surface markers, it is a member of the immunoglobulin superfamily.Synonyms: T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4

Gene ID: 920

NCBI Accession: NP_000607

UniProt: P01730

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events