Zinc Finger Protein 346 (104116) (C-Term) antibody

Details for Product No. ABIN783401
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Antigen
Synonyms ZNF346, jaz, zfp346, JAZ, Zfp346, Jaz, Znf346, im:7136406, wu:fc21c04, zgc:158750, DsRBP-ZFa, ZFa
Epitope
C-Term
(8), (7), (7), (7), (6), (2), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(53), (30), (22), (12), (12)
Host
Rabbit
(49), (4)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(43), (24), (10), (10), (4), (3), (3), (2), (1)
Pubmed 2 references available
Quantity 0.1 mg
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Catalog No. ABIN783401
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Immunogen 20 amino acid peptide near the carboxy terminus of human ZNF346
Specificity This antibody detects ZNF346 at C-term. Species Reactivity: Tested: Human, mouse
Purification Affinity chromatography purified via peptide column
Alternative Name ZNF346
Background ZNF346, also known as JAZ (just another zinc-finger protein), is a nucleolar, zinc finger protein which preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids with high affinity via C2H2 zinc fingers. ZNF346 contains four C(2)H(2)-type zinc finger motifs that are connected by long (28-38) amino acid linker sequences. ZNF346 is expressed in all tissues tested and localizes to the nucleus, primarily the nucleolus. ZNF346 is exported by exportin-5 but translocates back into nuclei by a facilitated diffusion mechanism. ZNF346 interacts with ILF3 in an RNA-independent manner and may be involved in cell growth and survival.
Alternate names: JAZ, Just another zinc finger protein, Zinc finger protein 346
Gene ID 23567
NCBI Accession NP_036411
UniProt Q9UL40
Research Area Chromatin and Nuclear Signaling, Chromatin Binding Proteins, DNA/RNA, Transcription Factors
Restrictions For Research Use only
Format Liquid
Buffer PBS containing 0.02% sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Expiry Date 12 months
Background publications Rosenfeld, Margalit: "Zinc fingers: conserved properties that can distinguish between spurious and actual DNA-binding motifs." in: Journal of biomolecular structure & dynamics, Vol. 11, Issue 3, pp. 557-70, 1994 (PubMed).

Simpson, Wellenreuther, Poustka et al.: "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing." in: EMBO reports, Vol. 1, Issue 3, pp. 287-92, 2001 (PubMed).

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