SCUBE1 antibody (Center)

Catalog No. ABIN783649

This Rabbit Polyclonal antibody specifically detects SCUBE1 in WB, IF and EIA. It exhibits reactivity toward Human.

Quick Overview for SCUBE1 antibody (Center) (ABIN783649)

Target: SCUBE1 (Signal Peptide, CUB Domain, EGF-Like 1 (SCUBE1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCUBE1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-SCUBE1 Antibody

Binding Specificity: Center

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Affinity chromatography purified via peptide column

Immunogen: 14 amino acid peptide near the center of human SCUBE1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: 14 amino acid peptide near the center of human SCUBE1

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for SCUBE1

Target: SCUBE1 (Signal Peptide, CUB Domain, EGF-Like 1 (SCUBE1))

Alternative Name: SCUBE1

Background: SCUBE1 is an EGF-related protein with a CUB (C1s-like) domain that is expressed primarily in the developing gonad, nervous system, somites, surface ectoderm and limb buds. The N-terminal EGF-like repeats of SCUBE1 participate in the formation of adhesions in a Ca2+-dependent fashion. In contrast, the C-terminal cysteine-rich motifs and CUB domain can directly bind and antagonize bone morphogenic protein activity, genetic ablation of this region resulted in brain malformation in mice embryos, suggesting SCUBE1 plays a role in brain morphogenesis. SCUBE1 has also been implicated in early craniofacial development in mice.Synonyms: Signal peptide CUB and EGF-like domain-containing protein 1

Gene ID: 80274

NCBI Accession: NP_766638

UniProt: Q8IWY4