PLAC1 antibody (C-Term)

Catalog No. ABIN783753

The Rabbit Polyclonal anti-PLAC1 antibody (ABIN783753) specifically detects PLAC1 in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for PLAC1 antibody (C-Term) (ABIN783753)

Target: PLAC1 (Placenta-Specific 1 (PLAC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLAC1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-PLAC1 Antibody

Binding Specificity: C-Term

Specificity: This antibody detects PLAC1 at C-term.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the carboxy terminus of human PLAC1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for PLAC1

Target: PLAC1 (Placenta-Specific 1 (PLAC1))

Alternative Name: PLAC1

Background: PLAC1 was initially identified as a protein expressed specifically in the placenta and other cells derived from the trophoblast lineage during embryonic development, but has also been found to be expressed ectopically in a wide range of human malignancies, particularly breast cancers. PLAC1 is a membrane-associated protein that is thought to serve a receptor-like function modulating cell-cell or ligand receptor interactions unique to the maternal-placental interface. Decreased expression of PLAC1 is associated with decreased expression of cyclin D1 and reduced expression of AKT kinase, which, combined with the fact that PLAC1 is expressed on the surface of cancer cells, suggests that PLAC1 may be an effective candidate for immunotherapeutic treatments of cancer.Synonyms: Placenta-specific protein 1

Gene ID: 10761

NCBI Accession: NP_068568

UniProt: Q9HBJ0