ODF2 antibody (Internal Region)

Catalog No. ABIN784271

The Goat Polyclonal anti-ODF2 antibody is suitable to detect ODF2 in samples from Human, Rat, Mouse, Dog and Pig. It has been validated for WB and EIA.

Quick Overview for ODF2 antibody (Internal Region) (ABIN784271)

Target: ODF2 (Outer Dense Fiber of Sperm Tails 2 (ODF2))

Reactivity: Human, Rat, Mouse, Dog, Pig

Host: Goat

Clonality: Polyclonal

Conjugate: This ODF2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-ODF2 Antibody

Binding Specificity: Internal Region

Sequence: C-REKHQASQKE NKQ

Specificity: This antibody is expected to recognize reported isoform 1 (NP_002531.3).

Cross-Reactivity (Details): Species reactivity (expected):Human, Rat, Canine (Dog), Pig.
Species reactivity (tested):Mouse.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_002531.3, NP_702915.1. Genename: ODF2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ODF2

Target: ODF2 (Outer Dense Fiber of Sperm Tails 2 (ODF2))

Alternative Name: ODF2

Background: Belongs to the ODF2 family. Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes. Required for the formation and/or maintenance of normal CETN1 assembly.Synonyms: Cenexin, Outer dense fiber of sperm tails protein 2, Outer dense fiber protein 2

Gene ID: 4957

NCBI Accession: NP_002531

Pathways: M Phase