PPY antibody (Internal Region)

Catalog No. ABIN784304

There are 3+ publications for this product available. The Goat Polyclonal anti-PPY antibody is suitable to detect PPY in samples from Human, Rat, Mouse and Dog. It has been validated for IHC (p) and EIA.

Quick Overview for PPY antibody (Internal Region) (ABIN784304)

Target: PPY (Pancreatic Polypeptide (PPY))

Reactivity: Human, Rat, Mouse, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This PPY antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-PPY Antibody

Binding Specificity: Internal Region

Sequence: C-TRPRYGKRHK EDT Remarks: Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Monkey (100%), Elephant (92%), Horse (92%), Marmoset (85%), Rat (85%), Sheep (85%), Bovine (85%).

Specificity: This antibody detects the internal region of PPY.

Cross-Reactivity (Details): Species reactivity (expected):Canine (Dog), Mouse and Rat.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogen: Synthetic peptide from the internal region of of Human PPY (NP_002713.1).

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline buffer, pH ~7.3 containing 0.5 % BSA as stabilizer and 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-PPY antibody (ABIN784304)

Nakajima, Nishitsuji, Kawashima, Kuwabara, Mikawa, Uchimura, Akaji, Kashiwada, Kobayashi, Saito, Sakashita: "The polyphenol (-)-epigallocatechin-3-gallate prevents apoA-IIowa amyloidosis in vitro and protects human embryonic kidney 293 cells against amyloid cytotoxicity." in: Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis, Vol. 23, Issue 1, pp. 17-25, (2016) (PubMed).

Hong, Liu, Fan, Chen, Chen, Zheng, Zhang, Gao, Zhu: "New perspectives of vesicular monoamine transporter 2 chemical characteristics in mammals and its constant expression in type 1 diabetes rat models." in: Translational research : the journal of laboratory and clinical medicine, Vol. 163, Issue 2, pp. 171-82, (2014) (PubMed).

Wang, Liu, Liu, Dong, Glickman, Slaga, Zhou, Liu: "Up-regulation of adiponectin by resveratrol: the essential roles of the Akt/FOXO1 and AMP-activated protein kinase signaling pathways and DsbA-L." in: The Journal of biological chemistry, Vol. 286, Issue 1, pp. 60-6, (2011) (PubMed).

Target Details for PPY

Target: PPY (Pancreatic Polypeptide (PPY))

Alternative Name: Pancreatic Prohormone

Background: Synonyms: Obinepitide, PNP, PPY, Pancreatic polypeptide

Gene ID: 5539

NCBI Accession: NP_002713

Pathways: Feeding Behaviour