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Details for Product No. ABIN785711

Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1) (C-Term) antibody

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Antigen
Synonyms Tdag, TDAG51, DT1P1B11, PHRIP
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Mouse (Murine), Rat (Rattus), Xenopus laevis, Cow (Bovine), Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN785711
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-PHLDA1 antibody: synthetic peptide directed towards the C terminal of human PHLDA1
Sequence LAVKSTRQKQQHLVQQQPPSQPQPQPQLQPQPQPQPQPQP QPQSQPQPQP
Predicted Reactivity African clawed frog : 100%, Bovine : 100%, Dog : 100%, Guinea pig : 100%, Horse : 100%, Human : 100%, Rabbit : 100%, Rat : 100%
Characteristics This is a rabbit polyclonal antibody against PHLDA1. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Affinity Purified
Alternative Name PHLDA1
Background PHLDA1 is an evolutionarily conserved proline-histidine rich nuclear protein. It may play an important role in the anti-apoptotic effects of insulin-like growth factor-1.This gene encodes an evolutionarily conserved proline-histidine rich nuclear protein. The encoded protein may play an important role in the anti-apoptotic effects of insulin-like growth factor-1.
Molecular Weight 45kDa
Gene ID 22822
NCBI Accession NP_031376, NM_007350
UniProt Q8WV24
Research Area Apoptosis/Necrosis
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-PHLDA1 antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Product cited in: Tsuda, Davis, Argani et al.: "TFE3 fusions activate MET signaling by transcriptional up-regulation, defining another class of tumors as candidates for therapeutic MET inhibition." in: Cancer research, Vol. 67, Issue 3, pp. 919-29, 2007 (PubMed).

Background publications Nagai, Fregnani, Netto et al.: "Down-regulation of PHLDA1 gene expression is associated with breast cancer progression." in: Breast cancer research and treatment, Vol. 106, Issue 1, pp. 49-56, 2007 (PubMed).

Alternatives for antigen "Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1)", type "Antibodies"
Hosts (29), (2)
Reactivities (29), (20), (20), (13), (12)
Applications (22), (10), (10), (3), (2), (2)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (3), (3), (2), (2), (1), (1), (1), (1), (1)
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