Glutathione Synthetase antibody

Catalog No. ABIN2722024

The Mouse Monoclonal anti-Glutathione Synthetase antibody is suitable to detect Glutathione Synthetase in samples from Human, Rat and Dog. It has been validated for WB and FACS.

Quick Overview for Glutathione Synthetase antibody (ABIN2722024)

Target: Glutathione Synthetase (GSS)

Reactivity: Human, Rat, Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This Glutathione Synthetase antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: 2G3

Product Details anti-Glutathione Synthetase Antibody

Characteristics: Homo sapiens glutathione synthetase (GSS)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human GSS (NP_000169) produced in HEK293T cell.

Isotype: IgG1

Application Details

Application Notes: WB 1:500~2000, FLOW 1:100

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for Glutathione Synthetase

Target: Glutathione Synthetase (GSS)

Alternative Name: GSS

Background: Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.

Molecular Weight: 52.2 kDa

Gene ID: 2937

NCBI Accession: NM_000178

HGNC: 2937

Pathways: Warburg Effect