Glutathione Synthetase antibody (AA 1-474)

Catalog No. ABIN5775948

This Mouse Monoclonal antibody specifically detects Glutathione Synthetase in WB, ICC, ELISA and IF. It exhibits reactivity toward Human.

Quick Overview for Glutathione Synthetase antibody (AA 1-474) (ABIN5775948)

Target: Glutathione Synthetase (GSS)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Glutathione Synthetase antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), ELISA, Immunofluorescence (IF)

Clone: AT12F2

Product Details anti-Glutathione Synthetase Antibody

Binding Specificity: AA 1-474

Purpose: Human Glutathione Synthetase/GSS antibody

Purification: Purified

Immunogen: Recombinant human GSS (1-474aa) purified from E. coli

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for Glutathione Synthetase

Target: Glutathione Synthetase (GSS)

Alternative Name: Glutathione Synthetase/GSS

Background: Glutathione synthetase, also known GSS, is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glycine, to form glutathione. Defects in GSS are the cause of glutathione synthetase deficiency (GSS deficiency) , also known as 5-oxoprolinuria or pyroglutamic aciduria. It is a severe form characterized by an increased rate of hemolysis and defective function of the central nervous system.

NCBI Accession: NP_000169

Pathways: Warburg Effect