MAPK7 antibody

Catalog No. ABIN2725432

The Mouse Monoclonal anti-MAPK7 antibody is suitable to detect MAPK7 in samples from Human. It has been validated for WB and IF.

Quick Overview for MAPK7 antibody (ABIN2725432)

Target: MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MAPK7 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: 5C7

Product Details anti-MAPK7 Antibody

Characteristics: Homo sapiens mitogen-activated protein kinase 7 (MAPK7), transcript variant 3

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human MAPK7 (NP_002740) produced in HEK293T cell.

Isotype: IgG1

Application Details

Application Notes: WB 1:2000, IF 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for MAPK7

Target: MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))

Alternative Name: MAPK7

Background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported.

Molecular Weight: 88.2 kDa

Gene ID: 5598

NCBI Accession: NM_002749

HGNC: 5598

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, cAMP Metabolic Process, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling