MEF2C antibody

Catalog No. ABIN2725763

The Mouse Monoclonal anti-MEF2C antibody is suitable to detect MEF2C in samples from Human. It has been validated for WB, IHC and FACS.

Quick Overview for MEF2C antibody (ABIN2725763)

Target: MEF2C (Myocyte Enhancer Factor 2C (MEF2C))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MEF2C antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 4G8

Product Details anti-MEF2C Antibody

Characteristics: Homo sapiens myocyte enhancer factor 2C (MEF2C), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human MEF2C(NP_002388) produced in HEK293T cell.

Isotype: IgG1

Application Details

Application Notes: WB 1:2000, IHC 1:150, FLOW 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for MEF2C

Target: MEF2C (Myocyte Enhancer Factor 2C (MEF2C))

Alternative Name: MEF2C

Background: This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins, which play a role in myogenesis. The encoded protein, MEF2 polypeptide C, has both trans-activating and DNA binding activities. This protein may play a role in maintaining the differentiated state of muscle cells. Mutations and deletions at this locus have been associated with severe mental retardation, stereotypic movements, epilepsy, and cerebral malformation. Alternatively spliced transcript variants have been described.

Molecular Weight: 51 kDa

Gene ID: 4208

NCBI Accession: NM_002397

HGNC: 4208

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, BCR Signaling