AP2M1 antibody (AA 97-383)

Catalog No. ABIN2716227

This Mouse Monoclonal antibody specifically detects AP2M1 in WB and IF. It exhibits reactivity toward Human, Mouse, Rat and Dog.

Quick Overview for AP2M1 antibody (AA 97-383) (ABIN2716227)

Target: AP2M1 (Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1))

Reactivity: Human, Mouse, Rat, Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This AP2M1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: 1C8

Product Details anti-AP2M1 Antibody

Binding Specificity: AA 97-383

Characteristics: Homo sapiens adaptor-related protein complex 2, mu 1 subunit (AP2M1), transcript variant 2

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Human recombinant protein fragment corresponding to amino acids 97-383 of human AP2M1(NP_001020376) produced in E.coli.

Isotype: IgG2a

Application Details

Application Notes: WB 1:500~2000, IF 1:100,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for AP2M1

Target: AP2M1 (Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1))

Alternative Name: AP2M1

Background: This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 49.2 kDa

Gene ID: 1173

NCBI Accession: NM_001025205

HGNC: 1173

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation, SARS-CoV-2 Protein Interactome