PSIP1 antibody

Catalog No. ABIN865479

The Mouse Monoclonal anti-PSIP1 antibody (Clone 6E4) (ABIN865479) specifically detects PSIP1 in WB, IHC, IF and ELISA. The antibody is reactive with Human, Rat and Monkey samples.

Quick Overview for PSIP1 antibody (ABIN865479)

Target: PSIP1 (PC4 and SFRS1 Interacting Protein 1 (PSIP1))

Reactivity: Human, Rat, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This PSIP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Clone: 6E4

Product Details anti-PSIP1 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human CARM1 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: WB: 1/500 - 1/2000, IHC:1/200-1/1000, IF: 1/200-1/1000, ELISA: Propose dilution 1/10000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100g/100l

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for PSIP1

Target: PSIP1 (PC4 and SFRS1 Interacting Protein 1 (PSIP1))

Alternative Name: PSIP1

Background: Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration. Tissue specificity: Widely expressed. Expressed at high level in the thymus. Expressed in fetal and adult brain. Expressed in neurons, but not astrocytes. Markedly elevated in fetal as compared to adult brain. In the adult brain, expressed in the subventricular zone (SVZ), in hippocampus, and undetectable elsewhere. In the fetal brain, expressed in the germinal neuroepithelium and cortical plate regions. Synonyms: p52, p75, PAIP, DFS70, LEDGF, PSIP2, MGC74712, PSIP1

Molecular Weight: 75kDa

Gene ID: 11168

Pathways: Chromatin Binding, Ribonucleoprotein Complex Subunit Organization