Osteoprotegerin antibody

Catalog No. ABIN865505

The Mouse Monoclonal anti-Osteoprotegerin antibody is suitable to detect Osteoprotegerin in samples from Human. It has been validated for WB, ELISA, IF and FACS.

Quick Overview for Osteoprotegerin antibody (ABIN865505)

Target: Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Osteoprotegerin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 5G2

Product Details anti-Osteoprotegerin Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human TNFRSF11B expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: WB: 1/500 - 1/2000, IF: 1/200 - 1/1000, FC: 1/200-1/400, ELISA: Propose dilution 1/10000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100g/100l

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for Osteoprotegerin

Target: Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))

Alternative Name: TNFRSF11B

Target Type: Chemical

Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. Synonyms: OPG, TR1, OCIF, MGC29565, TNFRSF11B

Molecular Weight: 60kDa

Gene ID: 4982