CD14 antibody

Catalog No. ABIN866061

The Rabbit Polyclonal anti-CD14 antibody (ABIN866061) specifically detects CD14 in WB. The antibody is reactive with Human samples.

Quick Overview for CD14 antibody (ABIN866061)

Target: CD14

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD14 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CD14 Antibody

Specificity: This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of CD14.

Cross-Reactivity: Human, Mouse (Murine)

Characteristics: Positive control: K562 cell lysate. Cellular Localization: Cell membrane

Purification: Immunogen affinity purified

Isotype: IgG

Application Details

Application Notes: WB: 1:1,000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 1xTBS (pH7.4), 0.5% BSA, 40% Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for CD14

Target: CD14

Alternative Name: CD14

Background: CD14 is a glycophosphatidylinositol-anchored protein expressed on the surfaces of monocytes and plymorphonuclear leukocytes. It cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). CD14 acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response and up-regulates cell surface molecules, including adhesion molecules.

Molecular Weight: 39kDa

UniProt: P10810

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades