ASPSCR1 antibody (AA 303-307)

Catalog No. ABIN871654

This Rabbit Polyclonal antibody specifically detects ASPSCR1 in WB. It exhibits reactivity toward Human.

Quick Overview for ASPSCR1 antibody (AA 303-307) (ABIN871654)

Target: ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASPSCR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ASPSCR1 Antibody

Binding Specificity: AA 303-307

Specificity: The antibody detects endogenous levels of total ASPSCR1 protein.

Purification: Affinity purified

Immunogen: Peptide sequence around AA 303-307 (P-Q-Q-E-Q) derived from Human ASPSCR1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Application Details

Application Notes: Western blotting: 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for ASPSCR1

Target: ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))

Alternative Name: ASPSCR1

Background: Tug (Tether containing UBX domain for GLUT4), also known as ASPL, ASPSCR1, RCC17, UBXD9, UBXN9, was first identified as a chromosomal translocation partner for TFE3 in patients with Alveolar soft part sarcoma and contains an UBX-like domain in its C-terminal region. Tug is found to tether GLUT4 in intracellular vesicles and to release GLUT4 for cell surface translocation upon insulin stimulation . Stable Tug depletion or expression of a dominant negative form stimulates GLUT4 redistribution.

Molecular Weight: 70-75 kDa

Gene ID: 79058

NCBI Accession: NP_076988

UniProt: Q9BZE9