ASPSCR1 antibody

Catalog No. ABIN1724649

Product Details anti-ASPSCR1 Antibody

Target: ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This ASPSCR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Purified

Immunogen: Purified recombinant fragment of TUG expressed in E. Coli.

Clone: 4A11A6G11

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: 4°C, -20°C for long term storage

References for anti-ASPSCR1 antibody (ABIN1724649)

Bogan, Hendon, McKee, Tsao, Lodish: "Functional cloning of TUG as a regulator of GLUT4 glucose transporter trafficking." in: Nature, Vol. 425, Issue 6959, pp. 727-33, (2003) (PubMed).

Target Details for ASPSCR1

Target: ASPSCR1 (Alveolar Soft Part Sarcoma Chromosome Region, Candidate 1 (ASPSCR1))

Alternative Name: TUG (ASPSCR1 Products)

Synonyms: tug antibody, aspl antibody, asps antibody, rcc17 antibody, ubxd9 antibody, aspcr1 antibody, ASPCR1 antibody, ASPL antibody, ASPS antibody, RCC17 antibody, TUG antibody, UBXD9 antibody, UBXN9 antibody, 1190006K01Rik antibody, ASPC antibody, ASPSCR1, UBX domain containing tether for SLC2A4 antibody, alveolar soft part sarcoma chromosome region, candidate 1 S homeolog antibody, alveolar soft part sarcoma chromosome region, candidate 1 antibody, alveolar soft part sarcoma chromosome region, candidate 1 (human) antibody, ASPSCR1 antibody, aspscr1.S antibody, Aspscr1 antibody, aspscr1 antibody, Bm1_55980 antibody

Background: The TUG protein contains a UBX domain, for GLUT4. In truncated form, TUG acts in a dominant-negative manner to inhibit insulin-stimulated GLUT4 redistribution in Chinese hamster ovary cells and 3T3-L1 adipocytes. Full-length TUG forms a complex specifically with GLUT4. In 3T3-L1 adipocytes, this complex is present in unstimulated cells and is largely disassembled by insulin. Endogenous TUG is localized with the insulin-mobilizable pool of GLUT4 in unstimulated 3T3-L1 adipocytes, and is not mobilized to the plasma membrane by insulin.

Gene ID: 79058

HGNC: 79058