TNFRSF10A antibody (C-Term)

Catalog No. ABIN925993

This Rabbit Polyclonal antibody specifically detects TNFRSF10A in WB. It exhibits reactivity toward Human.

Quick Overview for TNFRSF10A antibody (C-Term) (ABIN925993)

Target: TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNFRSF10A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TNFRSF10A Antibody

Binding Specificity: C-Term

Purification: Purified

Immunogen: TNFRSF10 A antibody was raised in rabbit using the C terminal of TNFRSF10 as the immunogen

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

TNFRSF10A Blocking Peptide, (ABIN5616705), is also available for use as a blocking control in assays to test for specificity of this TNFRSF10A antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for TNFRSF10A

Target: TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))

Alternative Name: TNFRSF10A

Background: This is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adaptor molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB. Synonyms: Polyclonal TNFRSF10A antibody, Anti-TNFRSF10A antibody, tumor necrosis factor receptor superfamily, member 10a antibody.

Pathways: Apoptosis, Positive Regulation of Endopeptidase Activity