Vinculin antibody (C-Term)

Catalog No. ABIN926662

This Rabbit Polyclonal antibody specifically detects Vinculin in WB. It exhibits reactivity toward Human.

Quick Overview for Vinculin antibody (C-Term) (ABIN926662)

Target: Vinculin (VCL)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Vinculin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Vinculin Antibody

Binding Specificity: C-Term

Purification: Purified

Immunogen: VCL antibody was raised in rabbit using the C terminal of VCL as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

VCL Blocking Peptide, (ABIN5616950), is also available for use as a blocking control in assays to test for specificity of this VCL antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for Vinculin

Target: Vinculin (VCL)

Alternative Name: VCL

Background: Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. Synonyms: Polyclonal VCL antibody, Anti-VCL antibody, vinculin antibody, CMD1W antibody, CMH15 antibody, MVCL antibody.

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2