UBE2V1 antibody (C-Term)

Catalog No. ABIN926783

The Rabbit Polyclonal anti-UBE2V1 antibody is suitable to detect UBE2V1 in samples from Human. It has been validated for WB.

Quick Overview for UBE2V1 antibody (C-Term) (ABIN926783)

Target: UBE2V1 (Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE2V1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-UBE2V1 Antibody

Binding Specificity: C-Term

Purification: Purified

Immunogen: UBE2 V1 antibody was raised in rabbit using the C terminal of UBE2 1 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

UBE2V1 Blocking Peptide, (ABIN936320), is also available for use as a blocking control in assays to test for specificity of this UBE2V1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for UBE2V1

Target: UBE2V1 (Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))

Alternative Name: UBE2V1

Background: Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Multiple alternatively spliced transcripts encoding different isoforms have been described for this gene. A pseudogene has been identified which is also located on chromosome 20. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. Synonyms: Polyclonal UBE2V1 antibody, Anti-UBE2V1 antibody, ubiquitin-conjugating enzyme E2 variant 1 antibody, CIR1 antibody, CROC-1 antibody, CROC1 antibody, UBE2V antibody, UEV-1 antibody, UEV1 antibody, UEV1A antibody.

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades