OAZ3 antibody (Middle Region)
Quick Overview for OAZ3 antibody (Middle Region) (ABIN928700)
Target
See all OAZ3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Purification
- Purified
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Immunogen
- OAZ3 antibody was raised in rabbit using the middle region of OAZ3 as the immunogen
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Application Notes
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. -
Comment
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OAZ3 Blocking Peptide, (ABIN937533), is also available for use as a blocking control in assays to test for specificity of this OAZ3 antibody
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Concentration
- Lot specific
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Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- OAZ3 (Ornithine Decarboxylase Antizyme 3 (OAZ3))
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Alternative Name
- OAZ3
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Background
- Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. In contrast to antizymes 1 and 2, which are widely expressed throughout the body, the expression of this gene product (antizyme 3) is restricted to testis germ cells, and thus it is a possible candidate for heritable forms of human male infertility. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Synonyms: Polyclonal OAZ3 antibody, Anti-OAZ3 antibody, ornithine decarboxylase antizyme 3 antibody, AZ3 antibody, OAZ-t antibody, TISP15 antibody.
Target
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