OAZ3 antibody (Middle Region)

Catalog No. ABIN2785531

This Rabbit Polyclonal antibody specifically detects OAZ3 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Guinea Pig, Dog, Horse, Pig and Rabbit.

Quick Overview for OAZ3 antibody (Middle Region) (ABIN2785531)

Target: OAZ3 (Ornithine Decarboxylase Antizyme 3 (OAZ3))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OAZ3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-OAZ3 Antibody

Binding Specificity: Middle Region

Purpose: OAZ3 Antibody - middle region

Sequence: DRRLFLDIPY QALDQGNRES LTATLEYVEE KTNVDSVFVN FQNDRNDRGA

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against OAZ3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human OAZ3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53713-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for OAZ3

Target: OAZ3 (Ornithine Decarboxylase Antizyme 3 (OAZ3))

Alternative Name: OAZ3

Background:

Background Information: Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. In contrast to antizymes 1 and 2, which are widely expressed throughout the body, the expression of this gene product (antizyme 3) is restricted to testis germ cells, and thus it is a possible candidate for heritable forms of human male infertility. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: Ornithine decarboxylase antizyme 3

Alternative Symbols: AZ3, OAZ-t, TISP15

Protein Name: Ornithine decarboxylase antizyme 3

Molecular Weight: 21kDa

Gene ID: 51686

NCBI Accession: NP_057262

UniProt: Q9UMX2